Thursday Night Football returns tonight with a primetime AFC matchup as the Buffalo Bills visit the Houston Texans at NRG Stadium. The NFL confirmed the Week 12 schedule earlier this week, and fans asking when is Thursday Night Football tonight have their answer: kickoff is set for 8:15 p.m. ET, airing exclusively on Prime Video, with mobile streaming available on NFL+.
The Bills enter the game at 7-3, while the Texans sit at 5-5 and fighting to stay in the AFC playoff race. Both teams are dealing with notable injuries that may impact strategy and personnel decisions.
Buffalo comes into Thursday Night Football riding momentum after a 44–32 win over Tampa Bay, powered by Josh Allen’s six-touchdown performance. However, the team remains shorthanded. Tight end Dalton Kincaid (hamstring) is out, along with receivers Curtis Samuel and Mecole Hardman.
Houston will continue without quarterback C.J. Stroud, who remains sidelined with a concussion, according to AP reports. Backup Davis Mills will start after guiding the Texans to a 16–13 victory over Tennessee in Week 11.
Both teams have won three of their last four, making this a pivotal clash for AFC position.
Analysts Weigh In
Analysts from ESPN and NFL Network highlighted the strategic adjustments tonight:
ESPN’s Jeremy Fowler noted, “Buffalo’s offense loses versatility without Kincaid, but Josh Allen remains one of the league’s most dangerous red-zone quarterbacks.”
NFL Network’s Cynthia Frelund added, “Houston’s secondary has been outstanding the past three weeks. Their ability to limit deep passing attempts will determine whether the Texans stay competitive.”
247Sports NFL analyst Garrett Podell said, “Davis Mills provides stability, but the Texans need to run the ball effectively to keep pace with Buffalo’s scoring potential.”
AFC Seeding and Week 12 Picture
Tonight’s matchup carries postseason implications across the AFC landscape.
A Bills win helps them strengthen their pursuit of top-tier AFC seeding, particularly with the East tightly contested. Without key receiving options, Buffalo will rely heavily on Allen’s mobility and improvisation.
Houston aims to climb above .500 and remain in the AFC South race. Their defensive growth over recent weeks continues to be a storyline, with young playmakers gaining confidence.
Thursday Night Football often sets the tone for the weekend slate, and this game is expected to influence Wild Card projections for both divisions.
Upcoming Announcements & Matchups
Following Thursday Night Football:
Buffalo prepares for a Week 13 divisional matchup with the New York Jets.
Houston travels to Indianapolis for a critical AFC South showdown.
The NFL will release updated playoff standings after the Thursday game concludes.
Prime Video is scheduled to announce its December TNF production enhancements later this week.
Sources
ESPN
247Sports
NFL Network
AP News
On3 Sports














